Nitidon, a new bioactive metabolite from the basidiomycete Junghuhnia nitida (Pers.: Fr.) Ryv.

The himanimides, new bioactive compounds from Serpula himantoides (Fr.) Karst.

In a screening of basidiomycete cultures from Chile for the production of antibiotics we identified a Serpula himantoides strain as a producer of metabolites inhibiting the growth of bacteria and fungi. Bioactivity guided purification resulted in the isolation of four new antibiotics. Their structures were elucidated by spectroscopic methods. All four compounds are succinimide and maleimide der...

Pulvinatal, a novel bioactive metabolite from the basidiomycete Nidularia pulvinata (Schw.) Fr.

Pulvinatal (1) was isolated from fermentations of Nidularia pulvinata as an inducer of differentiation of HL-60 promyelocytic leukemia cells. Its structure was elucidated by spectroscopic methods. In addition, N. pulvinata was found to produce 2,4,5-trihydroxy-6-methyl-benzenecarbaldehyde (2) and orsellinic acid (3). Pulvinatal exhibits weak antifungal and only marginal cytotoxic activities.

Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.

In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane ses...

Comparison between antioxidant activity and bioactive compounds of Ganoderma applanatum (Pers.) Pat. and Ganoderma lucidum (Curt.) P. Karst from Iran

Members of Ganoderma genus, belong to Basidiomycota, such as Ganoderma applanatum and Ganoderma lucidum have been noticed in traditional and modern medicine and pharmacology for their medicinal properties and bioactive compounds. The present study is undertaken to determine whether there is difference between chemical properties of G. applanatum and G. lucidum. The fresh mature fruiting bodies ...

بررسی امکان مبارزه بیولوژیکی با بیماری خال سیاه سیب زمینی بوسیله قارچ Trichoderma pers . ex Fr